Ethyl-p-aminobenzoate (Benzocaine) by Verdel K. Dawson Download PDF EPUB FB2
Ethyl-p-aminobenzoate (benzocaine) was tested for its efficacy as an anesthetic for rainbow trout (Salmo gairdnerii, brown trout (Salmo truttas, northern pike (Esox lucius). carp (Cyprinus carpio), and largemouth bass (Mieropterus salmoidesi.
Since benzocaine is not water soluble, it was applied with acetone as a carrier. Concentrations of to mg!l Ethyl-p-aminobenzoate book required for large adult northern. A strategy based on negative ion electrospray ionization tandem mass spectrometry and closed-ring labeling with both 8-aminopyrene-1,3,6-trisulfonate (APTS) and p-aminobenzoic acid ethyl ester (ABEE) was developed for linkage and Ethyl-p-aminobenzoate book determination.
The solubility of ethyl p-aminobenzoate (EPAB) was measured in six different alcohols (methanol, ethanol, n-propanol, n-butanol, isobutyl alcohol, isoamyl alcohol) within ( to ) K by the last solid disappearance method.
The solubility increases with increasing temperature. The decreasing order satisfies the following sequence: methanol > ethanol > n-propanol > n-butanol > isoamyl Cited by: 2.
Ethyl P-aminobenzoate. Benzocaine, USP BE | Benzocaine, USP is a mild local anesthetic. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part in FDA registered and inspected facilities.
Devise a synthesis of benzocaine, ethyl p-aminobenzoate (H 2 NC 6 H 4 CO 2 CH 2 CH 3), from benzene, Ethyl-p-aminobenzoate book alcohols, and any needed organic or inorganic reagents. Benzocaine is the active ingredient in the topical anesthetic Orajel (Section C)%(3). Search results for ethyl aminobenzoate at Sigma-Aldrich.
Compare Products: Select up to 4 products. *Please select more than one item to compare. About BENZOCAINE: Ethyl PABA is an ester of ethyl alcohol and p-aminobenzoic acid. Function(s): Ultraviolet Light Absorber Synonym(s): ETHYL PABA, 4-AMINO- ETHYL ESTER BENZOIC ACID; 4-AMINOBENZOIC ACID, ETHYL ESTER; BENZOIC ACID, 4-AMINO- ETHYL ESTER; BENZOIC ACID, 4AMINO, ETHYL ESTER; ETHYL 4-AMINOBENZOATE; ETHYL ESTER 4-AMINOBENZOIC ACID.
Ethyl p-acetamidobenzoate. IUPAC Name: ethyl 4-acetamidobenzoate. CAS Number: Chemical Formula: C 11 H 13 NO 3. click here for details. WEB SEARCH MSDS. Benzocaine is an ester of paraaminobenzoic acid, lacking the terminal diethylamino group of procaine, with anesthetic activity.
Benzocaine binds to the sodium channel and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of. Ethyl p-aminobenzoate (CAS NO.:), which is also known as, 4-amino- ethyl ester, could be produced through the following synthetic routes.
A solution of g. ( mole) of ethyl p-nitrobenzoate in cc. of 95 per cent alcohol is placed in the reaction bottle of the catalytic reduction apparatus (p.
61), and g. of platinum oxide. Separation of Benzoic acid, Ethyl p-aminobenzoate, and Benzoin. Using Ion-exchange Resins. Procedure: Dissolve a mixture of 25 mg each of the title compounds in 1 mL of ethanol.
Pass the solution over a set of two 8 mL SPE tubes, one loaded with 2ml of. It was revealed that p-aminobenzoate was oxidized to p-nitrobenzoate by Streptomyces l other aromatic nitro compounds such as p-aminobenzaldehyde and p-aminophenylacetate were oxidized in the same way although with a lower rate; however, others such as o-aminobenzoate, m-aminobenzoate, and p-aminophenol were not oxidized by the by: Benzocaine is the ethyl ester of 4-aminobenzoic acid ().
The classic, optimal way of benzocaine synthesis is the reduction of the nitro group of the ethyl ester of 4-nitrobenzoic acid to benzocaine by hydrogen, which generates directly in the reaction medium by the reaction of. (organic chemistry) C 6H 4NH 2CO 2 -C 2H 5 A white powder, melting point °C, slightly soluble in ethanol and ether, very slightly soluble in water; used as a local anesthetic.
Also known as benzocaine. The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication.
The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification.
Material Safety Data Sheet Version Revision Date 01/03/ Print Date 09/08/ 1. PRODUCT AND COMPANY IDENTIFICATION Product name: Ethyl 4-aminobenzoate Product Number: Brand: Sigma-Aldrich Company: Sigma-Aldrich Spruce Street SAINT LOUIS MO USA File Size: 29KB.
Compound Benzocaine with free spectra: 4 NMR, 5 FTIR, 1 Raman, and 2 MS. Toggle navigation Toggle search bar. Ethyl p-aminobenzoate 4-Aminobenzoic acid, ethyl ester p-Aminobenzoic acid, ethyl ester Journal or Book Year.
Ethyl p-aminobenzoate can be prepared by the esterification of p-aminobenzoic acid, 1 and by the reduction of ethyl p-nitrobenzoate with ammonium sulfide, 2 electrolytically, 3 and with tin and alcoholic hydrochloric acid.
4 Although the reducing agent used commercially is generally iron and water in the presence of a little acid, the catalytic reduction procedure described is by far the most. ethyl 4-aminobenzoate.
IUPAC Name: ethyl 4-aminobenzoate. CAS Number: Chemical Formula: C 9 H 11 NO 2. click here for details. WEB SEARCH MSDS. Incompatible with strong oxidizing agents. OU Chemical Safety Data (No longer updated) More details. OU Chemical Safety Data (No longer updated) More details. A benzoate ester having 4-aminobenzoic acid as the acid component and ethanol as the alcohol component.
A surface anaesthetic, it is used to suppress the gag reflex, and as a lubricant. 4-aminobenzoate is an aromatic amino-acid anion that is the conjugate base of 4-aminobenzoic acid.
It has a role as an Escherichia coli metabolite, a plant metabolite and a Saccharomyces cerevisiae metabolite. It is an aromatic amino-acid anion and an aminobenzoate. It derives from a benzoate. It is a conjugate base of a 4-aminobenzoic acid. Experiment 3. Ester Formation: Preparation of Benzocaine.
Esterification [see Ege’s: Sections B-D, pp ] H 3C OH O ace tic acid H3C-CH 2- O-H ethanol H+ Δ HC + CH2CH3 + H ehyl ac The experimental equilibrium constant for the reaction above is: [ethyl acetate] x File Size: KB.
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Get this from a library. Investigations in Fish Control: Ethyl-p-aminobenzoate (Benzocaine): efficacy as an anesthetic for five species of freshwater fish ; Influences of selected environmental factors on the activity of a prospective fish toxicant, 2-(Digeranylamino)-ethanol, in laboratory tests ; Toxicities of the lampricides 3-trifluoromethylnitrophenol (TFM) and the 2.
MSDS Name: Ethyl 4-aminobenzoate, 98% Catalog Numbers: AC, AC, AC, AC Synonyms: 4-Aminobenzoic acid ethyl ester. Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ Structure, properties, spectra, suppliers and links for: (2 H 5)Ethyl 4-aminobenzoate.
Both low- and high-resolution nanosecond-pulsed laser-induced fluorescence spectra of methyl and ethyl -aminobenzoate van der Waals complexes (MAB and EAB) have been characterised following jet-expansion investigations.
A combined MNDO–Lennard-Jones computation method has been used to determine the potential-energy. CSNpharm, Inc. is supplier for Ethyl 4-aminobenzoate.
We supply over bioactive compounds in stock, including inhibitors, agonists, natural products, PROTACTs and screening libraries for laboratory and scientific use. We have a professional technical support team for customer service with years of experience in life science.
Antipyrine and Benzocaine Otic Solution is an otic solution containing Antipyrine, Benzocaine, Oxyquinoline Sulfate, and Anhydrous Glycerin for use in the ear.
The solution congeals at 0°C (32°F), but returns to normal consistency, unchanged, at room temperature/. the stockroom caused the benzoic acid, benzocaine (ethyl p-aminobenzoate), and fluorenone to get mixed together. Your mission is to separate them. This will be done on a larger scale than the previous experiment, so you'll need to use a small separatory funnel ("sep funnel").
First, however, we need to be sure we understand the solubilities.Question about solubility. My experiments show that ethyl 4-aminobenzoate is insoluble in water, insoluble in 1M NaOH, and soluble in 1M HCl.
Shouldn't it dissolve in all 3 of these solvents? Doesn't the amine and ester group on the solute make the compound relatively .benzocaine: [ an″es-thet´ik ] 1. pertaining to, characterized by, or producing anesthesia.
2. a drug or agent used to abolish the sensation of pain, to achieve adequate muscle relaxation during surgery, to calm fear and allay anxiety, and to produce amnesia for the event.
Inhalational anesthetics are gases or volatile liquids that produce.